MULTISPECIFIC MODULAR ANTIBODY
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United States of America Patent
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app pub date -
Mar 29, 2012
filing date -
Jul 14, 2010
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Abstract
The invention relates to an antibody having at least two specificities to bind a glycoepitope and a receptor of the erbB class on the surface of a tumor cell, thereby crosslinking the glycoepitope and the receptor, which antibody has apoptotic activity effecting cytolysis independent of NK cells, a method of producing such antibody and its use as a therapeutic.
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