METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING DOWN SYNDROME

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United States of America Patent

APP PUB NO 20120277218A1
SERIAL NO

13497341

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The compounds and pharmaceutical compositions of the present invention are believed to significantly inhibit Dyrk 1a activity which suggests that the agents could provide therapeutic benefit for Down syndrome, since Dyrk 1a overproduction in Down syndrome appears to account for the developmental cognitive impairment and reduction in neurogenesis. The compounds and pharmaceutical compositions, administered during early post-natal development, may increase neurogenesis and thereby reduce cognitive impairment which may ultimately allow individuals with Down syndrome to live a more independent life.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
NEURONASCENT, INC.CLARKSVILLE, MD6

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kelleher-Andersson, Judith Clarksville, US 19 24

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