Methods for Decreasing Ocular Toxicity of Antibody Drug Conjugates
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United States of America Patent
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Issued Date -
Nov 8, 2012
app pub date -
Apr 4, 2012
filing date -
Apr 4, 2011
priority date (Note) -
Abandoned
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Abstract
The invention relates to charged or pro-charged cross-linking moieties and conjugates of cell binding agents and drugs comprising the charged or pro-charged cross-linking moieties and method of using the same to reduce ocular toxicity associated with administration of antibody drug conjugates.
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