Alpha-Amylase Mutants

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United States of America Patent

APP PUB NO 20120283164A1
SERIAL NO

13556623

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to a novel Termamyl-like alpha-amylase, and Termamyl-like alpha-amylases comprising mutations in two, three, four, five or six regions/positions. The variants have increased thermostability at acidic pH and/or at low Ca2+ concentrations (relative to the parent). The invention also relates to a DNA construct comprising a DNA sequence encoding an alpha-amylase variant of the invention, a recombinant expression vector which carries a DNA construct of the invention, a cell which is transformed with a DNA construct of the invention, the use of an alpha-amylase variant of the invention for washing and/or dishwashing, textile desizing, starch liquefaction, a detergent additive comprising an alpha-amylase variant of the invention, a manual or automatic dishwashing detergent composition comprising an alpha-amylase variant of the invention, a method for generating a variant of a parent Termamyl-like alpha-amylase, which variant exhibits increased thermostability at acidic pH and/or at low Ca2+ concentrations (relative to the parent).

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Patent Owner(s)

Patent OwnerAddress
NOVOZYMES A/S2880 BAGSVAERD

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bisgard-Frantzen, Henrik Bagsvaerd, DK 45 465
Borchert, Torben Vedel Copenhagen, DK 79 1088
Hedegaard, Lisbeth Sjodborg, DK 10 105
Neilsen, Vibeke Skovgaard Bagsvaerd, DK 1 3
Nielsen, Bjarne Ronfeldt Virum, DK 27 285
Outtrup, Helle Ballerup, DK 61 530
Svendsen, Allan Birkerod, DK 305 2381

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