VEGF-D/VEGFR2/3-MEDIATED REGULATION OF DENDRITES
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United States of America Patent
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Issued Date -
Dec 6, 2012
app pub date -
Jun 1, 2011
filing date -
Jun 1, 2011
priority date (Note) -
Abandoned
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Abstract
The present invention relates to methods for modulating, i.e. increasing or decreasing, the length and/or the complexity of the dendrites of a neuronal cell by influencing the amount of vascular endothelial growth factor D (VEGFD)-related signaling. The present invention further relates to methods for treating age- and/or disease-related cognitive dysfunctions, or for impairing the memory of a subject. Finally, the present invention relates to recombinant VEGFD (rVEGFD) for use in the treatment of age- and/or disease-related cognitive dysfunctions.
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