Detecting succinylacetone
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United States of America Patent
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Aug 20, 2013
Grant Date -
Dec 6, 2012
app pub date -
Aug 9, 2012
filing date -
May 4, 2007
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Abstract
This invention relates, inter alia, to detecting and/or measuring succinylacetone and one or more additional biological analytes using mass spectrometry, e.g., tandem mass spectrometry, by derivatizing succinylacetone in a sample by contacting the sample with an extraction solution comprising a C1-3 linear or branched chain monoalcohol and a strong base selected from the group consisting of hydrazine, a modified hydrazine, and hydroxylamine.
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