Heteroaromatic phenylimidazole derivatives as PDE10A enzyme inhibitors

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United States of America Patent

PATENT NO 9096589
APP PUB NO 20120309714A1
SERIAL NO

13513867

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Abstract

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This invention is directed to compounds, which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.

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Patent Owner(s)

  • H. LUNDBECK A/S

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kehler, Jan Lyngby, DK 79 392
Kilburn, John Paul Haslev, DK 41 313
Langgård, Morten Glostrup, DK 46 279
Marigo, Mauro Skovlunde, DK 55 305
Nielsen, Jacob København V, DK 60 507
Püschl, Ask Frederiksberg, DK 14 60

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