Assay for Metastatic Colorectal Cancer
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United States of America Patent
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Issued Date -
Dec 20, 2012
app pub date -
May 25, 2012
filing date -
Oct 27, 2006
priority date (Note) -
Abandoned
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Abstract
Disclosed herein is a method for predicting the prognosis, the likelihood of metastasis in, or the desirability of administering an aggressive therapy to, a subject with colorectal cancer, comprising determining, in a sample from the subject, the level of phosphorylation of one or more of certain proteins compared to a positive and/or negative reference standard; or the total amount of COX-2 protein compared to a positive and/or negative reference standard. Also described are methods for treating subjects likely to develop metastatic colorectal carcinoma, and pharmaceutical compositions and kits for implementing the methods of the invention.
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