SUBSTITUTED 2-INDOLINONE AS PTK INHIBITORS CONTAINING A ZINC BINDING MOIETY

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United States of America Patent

APP PUB NO 20120322844A1
SERIAL NO

13592956

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to substituted 2-indolinone containing zinc-binding moiety based derivatives that have enhanced or unique properties as inhibitors of protein tyrosine kinase (PTK) receptors and their use in the treatment of PTK related diseases and disorders such as cancer. The said derivatives may further act as HDAC inhibitors.

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Patent Owner(s)

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CURIS INC128 SPRING ST BUILDING C - SUITE 500 LEXINGTON MA 02421

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cai, Xiong Bedford, US 100 1263
Gould, Stephen San Carlos, US 51 1404
Qian, Changgeng Wayland, US 73 747

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