MODIFIED VACCINIA ANKARA VIRUS VARIANT

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United States of America Patent

SERIAL NO

13588217

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Abstract

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The present invention provides an attenuated virus, which is derived from Modified Vaccinia Ankara virus, wherein the MVA-BN virus, or a derivative thereof, induces at least substantially the same level of immunity in vaccinia virus prime/vaccina virus boost regimes when compared to DNA prime/vaccinia virus boost regimes. It further describes recombinant viruses derived from this virus and the use of the virus, or its recombinants, as a medicament or vaccine. A method is provided for inducing an immune response in individuals who may be immune-compromised, receiving antiviral therapy, or have a pre-existing immunity to the vaccine virus.

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Patent Owner(s)

Patent OwnerAddress
BAVARIAN NORDIC A/SHELLERUP

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHAPLIN, PAUL GRAFELFING, DE 49 764
HOWLEY, PAUL BERWICK, AU 59 800
MEISINGER-HENSCHEL, CHRISTINE NEURIED, DE 18 237

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