MODIFIED OLIGONUCLEOTIDES FOR TELOMERASE INHIBITION

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United States of America Patent

SERIAL NO

13590532

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Abstract

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Compounds comprising an oligonucleotide moiety covalently linked to a lipid moiety are disclosed. The oligonucleotide moiety comprises a sequence that is complementary to the RNA component of human telomerase. The compounds inhibit telomerase activity in cells with a high potency and have superior cellular uptake characteristics.

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Patent Owner(s)

Patent OwnerAddress
GERON CORPORATION919 E HILLSDALE BLVD SUITE 250 FOSTER CITY CA 94404

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
GRYAZNOV, Sergei San Mateo, US 60 744
Pongracz, Krisztina Oakland, US 37 447

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