Methods for Enhancing Natural Killer Cell Proliferation and Activity
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United States of America Patent
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Dec 29, 2010
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Dec 29, 2009
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Abstract
Methods of ex-vivo culture of natural killer (NK) cells are provided and, more particularly, methods for enhancing propagation and/or functionality of NK cells by treating the cells with a nicotinamide or other nicotinamide moiety in combination with cytokines driving NK cell proliferation. Also envisioned are compositions comprising cultured NK cells and therapeutic uses thereof.
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