BENZAZEPINE COMPOUND

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United States of America Patent

APP PUB NO 20130012496A1
SERIAL NO

13583410

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided is a compound which is useful as an agent for treating or preventing 5-HT2C receptor-related diseases, particularly incontinence such as stress urinary incontinence, urge urinary incontinence, mixed urinary incontinence, and the like, sexual dysfunction such as erectile dysfunction syndrome and the like, obesity, and the like. The present inventors have investigated compounds having a 5-HT2C receptor agonist activity and have found that the benzazepine compounds of the present invention have an excellent 5-HT2C receptor agonist activity, thereby completing the present invention. That is, the benzazepine compounds of the present invention have a 5-HT2C receptor agonist activity and can be used as an agent for treating or preventing 5-HT2C receptor-related diseases, particularly incontinence such as stress urinary incontinence, urge urinary incontinence, mixed urinary incontinence, and the like, sexual dysfunction such as erectile dysfunction syndrome and the like, obesity, and the like.

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Patent Owner(s)

Patent OwnerAddress
ASTELLAS PHARMA INCCHUO-KU TOKYO 103-8411

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Asai, Norio Tokyo, JP 19 193
Kawabata, Keiko Tokyo, JP 7 32
Koshio, Hiroyuki Tokyo, JP 25 140
Nagai, Yasuhito Tokyo, JP 7 0
Shimizu, Takafumi Tokyo, JP 27 126
Takahashi, Taisuke Tokyo, JP 24 61
Thor, Karl Bruce Durham, US 37 191

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