METHODS AND COMPOSITIONS FOR DRYING IN THE PREPARATION OF RADIOPHARMACEUTICALS

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United States of America Patent

APP PUB NO 20130022525A1
SERIAL NO

13550188

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method of drying a radioisotope solution having radioisotopes includes passing the radioisotope solution through a solid phase extraction column containing an anion exchange group, thereby trapping the radioisotopes in the column. The method also includes passing an eluent through the column, thereby removing the radioisotopes from the column. The eluent includes a cation trapping agent/salt complex, less than 4% water, and the remainder is a solvent. A method of producing the eluent includes reacting a cation trapping agent with a salt in the presence of less than 4% water and a solvent to form solubilized cation trapping agent/salt complex, wherein one of the cation trapping agent and the salt is present in en excess of a stoichiometric amount and ending the reaction when a predetermined amount of solubilized cation trapping agent/salt complex has been formed.

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Patent Owner(s)

Patent OwnerAddress
CARDINAL HEALTH 414 LLC7000 CARDINAL PLACE DUBLIN OH 43017

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Benecke, Herman Columbus, US 8 170
Bouton, Chad E Powell, US 69 4660
ESHIMA, Dennis B Phoenix, US 1 16
Garbark, Daniel B Blacklick, US 40 460
Husnu, Mehmet Phoenix, US 13 382
Klausing, Thomas A Powell, US 25 878
Padgett, Henry Hermosa Beach, US 5 124

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