Amide derivatives bearing a cyclopropylaminoacarbonyl substituent useful as cytokine inhibitors

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United States of America Patent

PATENT NO 8742124
APP PUB NO 20130035346A1
SERIAL NO

13628958

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Abstract

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The invention concerns a compound of the Formula (I), wherein Qa is heteroaryl and is substituted with halogeno; R1 and R2 are hydrogen; and Qb is phenyl or heteroaryl, and Qb may optionally bear 1 or 2 substituents selected from hydroxy, halogeno and (1-6C)alkyl, or a pharmaceutically-acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.

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Patent Owner(s)

Patent OwnerAddress
ASTRAZENECA ABSE-151 85 SODERTALJE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brown, Dearg Sutherland Macclesfield, GB 9 78
Cumming, John Graham Macclesfield, GB 7 110
Nash, Ian Alun Macclesfield, GB 15 31

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