Elimination of N-glycolylneuraminic acid from animal products for human use

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United States of America Patent

PATENT NO 8541231
APP PUB NO 20130039991A1
SERIAL NO

13528507

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Abstract

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The application is in the field of transgenic (non-human) organisms, sialic acid chemistry, metabolism and antigenicity. More particularly, the invention is related to a method to produce Neu5Gc-free animals and products therefrom comprising disrupting the CMAH gene and thereby reducing or eliminating Neu5Gc from biological material of non-humans.

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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA1111 FRANKLIN STREET TWELFTH FLOOR OAKLAND CA 94607-5200

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hedlund, Anna Maria San Diego, US 4 58
Nguyen, Dzung San Diego, US 15 296
Varki, Ajit La Jolla, US 28 219

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