Gammaretrovirus Associated With Cancer

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United States of America Patent

SERIAL NO

13551286

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Abstract

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The present invention provides for isolated nucleic acid sequences encoding viruses; isolated polypeptides comprising amino acid sequences of the virus; vectors comprising the viral nucleic acid sequences; cells comprising the vectors; antibodies and antigen binding fragments thereof which have binding specificity for the virus; methods of detecting or screening for the virus (e.g., in an individual); methods of identifying agents that inhibit the virus; methods of inducing an immune response to the virus; methods of treating disease associated with the presence of XMRV in an individual (e.g., cancer such as prostate cancer); methods of detecting asymptomatic cancer (e.g., prostate cancer); methods of identifying an individual at risk for developing cancer (e.g., prostate cancer); and kits for detecting the virus.

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Patent Owner(s)

Patent OwnerAddress
THE CLEVELAND CLINIC FOUNDATION9500 EUCLID AVENUE CLEVELAND OH 44195

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Casey, Graham Pasadena, US 6 10
DeRisi, Joseph San Francisco, US 3 5
Ganem, Don San Francisco, US 2 1
Klein, Eric A Shaker Heights, US 12 518
Silverman, Robert H Beachwood, US 21 109

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