DIAGNOSTIC AND THERAPEUTIC METHODS FOR CORNEAL ECTASIA FOLLOWING REFRACTIVE SURGERY, KERATOCONUS OR PELLUCID DEGENERATION

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Mar 7, 2013
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Dec 2, 2010
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Dec 2, 2009

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Abstract

The present invention relates to methods of diagnosis and treatment of corneal ectasia following refractive surgery, keratoconus or pellucid marginal degeneration in a subject by determining or modulating the level of expression of molecules associated with the Wnt signalling pathway. Marker molecules of the present invention include SFRP1, PITX2, LEF1, WNT16 and WNT5A.

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THE UNIVERSITY OF SYDNEY	SYDNEY NEW SOUTH WALES

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Inventor Name	Address	# of filed Patents	Total Citations
Madigan, Michele	Hurlstone Park, AU	2	11
McAvoy, John	Stanmore, AU	5	85
Sutton, Gerard	Balmoral, AU	5	5

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DIAGNOSTIC AND THERAPEUTIC METHODS FOR CORNEAL ECTASIA FOLLOWING REFRACTIVE SURGERY, KERATOCONUS OR PELLUCID DEGENERATION

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United States of America Patent

13513800

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