INFECTION ACTIVATED WOUND CARING COMPOSITIONS AND DEVICES
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United States of America Patent
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Issued Date -
Mar 14, 2013
app pub date -
Sep 7, 2012
filing date -
Sep 8, 2011
priority date (Note) -
Abandoned
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Abstract
Provided are wound caring compositions and devices containing a pH-sensitive, preferably acid degradable, components contained in a water-permeable and hydronium ion permeable material. The pH-sensitive component encloses an antibiotic which is released to the wound upon infection by a microorganism at the wound site, and/or encloses a pH indicator. The antibiotic release is triggered by the microorganism's production of CO2 at the wound site which forms carbonic acid, lowers the pH at the pH sensitive components, and thus results in rupture of the liposome.
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