Use of G-clamp for improved allele-specific PCR

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United States of America Patent

PATENT NO 9476091
APP PUB NO 20130078630A1
SERIAL NO

13624077

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Abstract

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The present invention includes a method of allele-specific amplification, utilizing an allele-specific oligonucleotide, at least partially complementary to more than one variant of the target sequence, but having at least one selective nucleotide complementary to only one variant of the target sequence and incorporating at least one “G-clamp” nucleotide.

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Patent Owner(s)

Patent OwnerAddress
ROCHE MOLECULAR SYSTEMS INC4300 HACIENDA DRIVE PLEASANTON CA 94588

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bodepudi, Veeraiah San Ramon, US 17 254
Schoenbrunner, Nancy Moraga, US 34 92
Tsan, Alison Castro Valley, US 22 42

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