SYSTEM AND METHOD OF DETECTING AND CORRECTING FOR NUCLEIC ACID DAMAGE
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United States of America Patent
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Issued Date -
Mar 28, 2013
app pub date -
Sep 24, 2012
filing date -
Sep 23, 2011
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Abandoned
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Abstract
The present disclosure describes a method to estimate a geometric parameter to describe the degradation pattern (i.e. the proportion of bases that are damaged) in a sample. Using the values provided by the described systems and methods, researchers can estimate the proportion of undamaged fragments that are a certain base pairs in length or can estimate the number of errors within a fragment of certain base pairs in length.
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