Methods of identifying agents that diminish cellular toxicity associated with an α-synuclein polypeptide of parkinson's disease in yeast

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United States of America Patent

PATENT NO 8735072
APP PUB NO 20130084596A1
SERIAL NO

13418848

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Abstract

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Methods of screening candidate agents to identify lead compounds for the development of therapeutic agents for the treatment of a neurodegenerative disease, such as Huntington's Disease and Parkinson's Disease and methods for identifying a mutation in, or changes in expression of, a gene associated with neurodegenerative disease, such as Huntington's Disease and Parkinson's Disease, are provided.

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Patent Owner(s)

Patent OwnerAddress
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH455 MAIN STREET CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lindquist, Susan L Chestnut Hill, US 34 256
Muchowski, Paul J Kenmore, US 10 65
Outeiro, Tiago Lisbon, PT 9 80

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