Fibroblast growth factor 21 variants having improved pharmacological potency and/or improved pharmaceutical stability
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United States of America Patent
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Sep 24, 2013
Grant Date -
Apr 4, 2013
app pub date -
Sep 25, 2012
filing date -
Oct 4, 2011
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Abstract
This present invention relates to pharmacologically potent and/or stable variants of human fibroblast growth factor 21 (FGF21), pharmaceutical compositions comprising FGF21 variants, and methods for treating type 2 diabetes, obesity, dyslipidemia, or metabolic syndrome, or any combination thereof, using such variants.
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