RON Binding Constructs and Methods of Use Thereof
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United States of America Patent
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Issued Date -
Apr 11, 2013
app pub date -
Dec 29, 2010
filing date -
Dec 29, 2009
priority date (Note) -
Abandoned
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Abstract
This disclosure provides immunoglobulin binding molecules that specifically bind to human macrophage stimulating receptor (MST1 R, also referred to herein as recepteur d'origine Nantaise or RON), including antibodies and monospecific and multispecific single chain binding proteins having one or more other domains, such as one or more antibody constant region domains. Also provided are therapeutic applications of such binding proteins, such as for the treatment of cancer and inflammatory disorders.
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