Pan-lyssavirus vaccines against rabies

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United States of America Patent

PATENT NO 9248179
APP PUB NO 20130095137A1
SERIAL NO

13806622

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Abstract

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Described herein are recombinant rabies viruses encoding rabies virus glycoprotein and at least one heterologous glycoprotein from another lyssavirus, such as Mokola virus, Lagos bat virus and/or West Caucasian bat virus. In particular embodiments, the recombinant rabies virus includes two or three heterologous lyssavirus glycoproteins. The disclosed recombinant rabies viruses can be used as pan-lyssavirus vaccines to provide protection against lyssaviruses that cause rabies.

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Patent Owner(s)

Patent OwnerAddress
THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES CENTERS FOR DISEASE CONTROL AND PREVENTION4770 BUFORD HWY (K79) TECHNOLOGY TRANSFER OFFICE ATLANTA GA 30341

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kuzmin, Ivan V Lilburn, US 3 6
Rupprecht, Charles E Lawrenceville, US 5 15
Wu, Xianfu Atlanta, US 8 12

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