Methods of identifying interactions between genomic loci

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United States of America Patent

PATENT NO 9434985
SERIAL NO

13121158

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Abstract

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The disclosed Hi-C protocol can identify genomic loci that are spatially co-located in vivo. These spatial co-locations may include, but are not limited to, intrachromosomal interactions and/or interchromosomal interactions. Hi-C techniques may be applied to many different scales of interest. For example, on a large scale, Hi-C techniques can be used to identify long-range interactions between distant genomic loci.

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Patent Owner(s)

Patent OwnerAddress
PRESIDENT AND FELLOWS OF HARVARD COLLEGE17 QUINCY STREET CAMBRIDGE MA 02138
MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVE CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dekker, Job Princeton, US 9 81
Giannoukos, Georgia Cambridge, US 6 48
Gnirke, Andreas Wellesley, US 29 496
Lander, Eric Cambridge, US 15 166
Lieberman, Erez Cambridge, US 85 1444
Melnikov, Alexandre Bellingham, US 8 85
Nusbaum, Chad Nowtoa, US 8 271
Van, Berkum Nynke The Hague, NL 4 45
Williams, Louise Reading, US 5 64

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