Delivery of H2 Antagonists
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United States of America Patent
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Issued Date -
May 2, 2013
app pub date -
Dec 5, 2012
filing date -
Dec 29, 2004
priority date (Note) -
Abandoned
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Abstract
The present invention provides improved systems and methods for the local delivery of H2 antagonists. The inventive methods include topical administration of an effective amount of a H2 antagonist encapsulated in liposomes. In certain embodiments, the H2 antagonist, for example, Cimetidine, is encapsulated into paucilamellar liposomes, such as NOVASOME® microvesicles. Also provided are pharmaceutical compositions comprising liposome-encapsulated H2 antagonists. The methods and compositions of the present invention may be used to treat any disease state or condition where local administration of H2 antagonists is beneficial.
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