Device to expose cells to fluid shear forces and associated systems and methods
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United States of America Patent
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Sep 22, 2015
Grant Date -
May 2, 2013
app pub date -
Oct 29, 2012
filing date -
Oct 27, 2011
priority date (Note) -
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Abstract
The present technology relates generally to devices to expose cells to fluid shear forces and associated systems and methods. In particular, several embodiments are directed toward devices to expose cells to fluid shear forces in order to measure changes in internal cell forces. In some embodiments, a fluidic device includes a flow unit configured to induce fluid flow through the device. The device further includes a fluid channel configured to accept a biological sample dispersed on an array of flexible structures. The flow unit can be configured to induce disturbed and/or laminar flow in the fluid channel. The device can further include optical or magnetic detection means configured to measure a degree of deflection of one or more flexible structures in the array.
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