METHODS FOR DETECTING MUTATIONS
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United States of America Patent
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Issued Date -
May 2, 2013
app pub date -
Oct 26, 2012
filing date -
Oct 28, 2011
priority date (Note) -
Abandoned
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Abstract
The invention generally relates to methods for detecting mutations in a nucleic acid. In certain embodiments, the invention provides methods that involve forming a plurality of droplets, such that on average, each droplet includes a ratio of one nucleic acid template per bead, amplifying the template in the droplet to produce bead-bound amplicons, and sequencing at least one amplicon detect a mutation.
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