Azetidine compounds, compositions and methods of use

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United States of America Patent

PATENT NO 8809552
APP PUB NO 20130109668A1
SERIAL NO

13661072

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Abstract

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Provided are compounds of Formula I,

description='In-line Formulae' end='lead'R1-L1-A-L2-R2  (I),description='In-line Formulae' end='tail'

and stereoisomers, tautomers and pharmaceutically acceptable salts thereof, wherein A, L1, L2, R1 and R2 are defined herein. The present invention also provides a pharmaceutical composition and methods of using such compounds. The compounds are useful for therapy and/or prophylaxis in a patient, and in particular to inhibitors of Soluble Epoxide Hydrolase (sEH).

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Patent Owner(s)

Patent OwnerAddress
HOFFMANN-LA ROCHE INC150 CLOVE ROAD OVERLOOK AT GREAT NOTCH SUITE 8 LITTLE FALLS NJ 07424

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ceccarelli, Simona M Basel, CH 28 195
Guerot, Carine St. Albans, GB 2 4
Knust, Henner Rheinfelden, DE 83 353

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