Methods for using a nanopore
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United States of America Patent
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Aug 28, 2018
Grant Date -
May 16, 2013
app pub date -
Sep 13, 2012
filing date -
Apr 4, 2007
priority date (Note) -
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Abstract
Devices and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a nanopore are provided. The devices and methods also determine (˜>50 Hz) the nucleotide base sequence of a polynucleotide under feedback control or using signals generated by the interactions between the polynucleotide and the nanopore. The invention is of particular use in the fields of molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof.
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