Complex mutations in the epidermal growth factor receptor kinase domain

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United States of America Patent

PATENT NO 9738935
APP PUB NO 20130121996A1
SERIAL NO

13664333

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Abstract

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Six new mutations were found in exon 19 of the EGFR gene, the exon that is often mutated in tumors. The invention comprises methods of detecting the mutations, methods of prognosis and methods of predicting response to treatment based on the presence of absence of the mutations.

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Patent Owner(s)

  • ROCHE MOLECULAR SYSTEMS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Liu, Wei-min Dublin, US 54 384
Tsan, Alison Castro Valley, US 22 42

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