Anti-ferroportin 1 monoclonal antibodies and uses thereof
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United States of America Patent
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Mar 25, 2014
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N/A
app pub date -
May 7, 2012
filing date -
Dec 5, 2008
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Abstract
Provided are monoclonal antibodies and antigen-binding fragments thereof that bind to, and inhibit the activity of human FPN1, and which are effective in maintaining or increasing the transport of iron out of mammalian cells and/or maintaining or increasing the level of serum iron, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a subject in vivo.
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