FLUORESCENCE IMAGING APPARATUS AND METHOD
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United States of America Patent
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Issued Date -
May 23, 2013
app pub date -
Jan 24, 2011
filing date -
Jan 22, 2010
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Abandoned
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Abstract
A fluorescence emission imaging method and apparatus allows for high frame rate imaging in scattering medium as well as for fluorescence, phosphorescence, or luminescence lifetime imaging, time-resolved fluorescence, phosphorescence, or luminescence lifetime spectroscopy and imaging. A method involves providing an illumination beam, propagating the illumination beam to a light modulator array, modulating the illumination beam so as to generate an array of point sources, wherein each of the point sources is modulated at a frequency, imaging the modulated illumination beam on the object, and detecting a fluorescent, phosphorescent, or luminescent emission from the object. An optical imaging component in the form of a modulation mask has multiple bands. Each band has alternating transmissive and/or reflective and/or absorptive regions that are patterned such that light scanned over a band will be modulated at a band-related frequency.
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