NOVEL CONDITIONALLY IMMORTALIZED HUMAN PROXIMAL TUBULE CELL LINE EXPRESSING FUNCTIONAL INFLUX AND EFFLUX TRANSPORTERS
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United States of America Patent
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Issued Date -
May 23, 2013
app pub date -
Nov 4, 2010
filing date -
Nov 4, 2009
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Abandoned
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Abstract
The invention relates to the field of biology and medicine. In particular, the invention relates to the field of pharmaceutical research and drug development, and especially to means for physiological, pharmacological and toxicological research. More in particular, the invention provides renal cell lines with proximal tubular characteristics including multiple influx and efflux transporters. These cell lines are termed ciPTEC. Four representative examples have been deposited at the Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH (DSMZ or German Collection of Microorganisms and Cell Cultures) at Inhoffenstrasse 7 B, 38124 Braun-schweig, Germany under accession number DSM ACC3019, DSM AC-C3020, DSM ACC3021 and DSM ACC3022.
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