DETECTION METHOD OF NOVEL RET FUSION
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United States of America Patent
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Issued Date -
May 30, 2013
app pub date -
Jul 22, 2011
filing date -
Jul 26, 2010
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
It was found that a new fusion gene of a portion of the KIF5B gene and a portion of the RET gene, which is present in a portion of cancer patients, is a gene responsible for cancer. Based on this finding, detection methods of a polynucleotide as the gene and a polypeptide encoded by the polynucleotide were established. The detection methods involve detecting a fusion gene of a portion of the KIF5B gene and a portion of the RET gene, or a fusion protein encoded by such a fusion gene. The primer sets and the detection kits comprise sense primers designed from a portion encoding KIF5B and antisense primers designed from a portion encoding RET.
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