HEPARAN SULFATE REPLACEMENT THERAPY
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United States of America Patent
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Issued Date -
Jun 6, 2013
app pub date -
Mar 11, 2011
filing date -
Mar 12, 2010
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a method for inhibiting oxidative damage of islet beta cells in vivo in a subject by administering to the subject a therapeutically effective amount of heparan sulfate capable of protecting islet beta cells from reactive oxygen species or in vitro by exposing isolated islet beta cells, prior to transplantation, to a concentration of heparan sulfate that protects them from reactive oxygen species.
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