Labeled alginate conjugates for molecular imaging applications
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United States of America Patent
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Mar 10, 2015
Grant Date -
Jun 13, 2013
app pub date -
Dec 7, 2012
filing date -
Dec 9, 2011
priority date (Note) -
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Abstract
Described are bifunctional NOTA-based derivatives capable of conjugating with alginate and with metal ions, as well as NOTA-alginate conjugates which can be labeled with stable or radioactive metal ions. Also described are conjugation methods of the bifunctional NOTA-based linker with alginate, and methods of using radiometal-labeled NOTA-alginate conjugates or other radio-labeled alginate conjugates as imaging reagents.
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International Classification(s)
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C07F:ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CO....
- C07D:HETEROCYCLIC COMPOUNDS
- C07B:GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS TH....
- C08B:POLYSACCHARIDES; DERIVATIVES THEREOF
- A61M:DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE B....
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