Cyclized peptidomimetic small molecule inhibitors of the WDR5 and MLL1 interaction

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United States of America Patent

PATENT NO 8980838
APP PUB NO 20130150309A1
SERIAL NO

13686475

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Abstract

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Cyclic peptidomimetics that inhibit the interaction between MLL1 and WDR5 are disclosed. Methods of inhibiting MLL1 activity and methods of treating cancers also are disclosed.

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Patent OwnerAddress
THE REGENTS OF THE UNIVERSITY OF MICHIGAN1600 HURON PARKWAY 2ND FLOOR ANN ARBOR MI 48109-2590

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bernard, Denzil Ann Arbor, US 7 3
Cao, Fang Ann Arbor, US 22 29
Dou, Yali Ann Arbor, US 3 1
Karatas, Hacer Ann Arbor, US 5 57
Townsend, Elizabeth Ann Arbor, US 4 1
Wang, Shaomeng Saline, US 129 1098

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