RECOMBINANT PHYCOBILIPROTEINS WITH ENHANCED FLUORESCENCE AND PHOTOCHEMICAL PROPERTIES
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United States of America Patent
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Issued Date -
Jul 4, 2013
app pub date -
Sep 8, 2011
filing date -
Sep 8, 2010
priority date (Note) -
Abandoned
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Abstract
Novel fluorescent phycobiliprotein fusion proteins and methods of use are described. The novel phycobiliproteins can be produced in a cell comprising two or more heterodimeric lyases, an apoprotein and a bilin reductase, which components react to form the phycobiliprotein fusion protein. Also described are phycobiliprotein based transcription reporter cells and assays, which cells conditionally express a heterologous, fluorescent, phycobiliprotein domain even in anoxic conditions.
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