COMPOSITION FOR TOPICAL TREATMENT OF MIXED VAGINAL INFECTIONS
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United States of America Patent
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Issued Date -
Jul 4, 2013
app pub date -
Jul 25, 2012
filing date -
Sep 19, 2003
priority date (Note) -
Abandoned
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Abstract
A pharmaceutical composition comprises (a) an antibacterial agent in an antibacterially effective amount, illustratively comprising clindamycin or a pharmaceutically acceptable salt or ester thereof; and (b) an antifungal agent in an antifungally effective amount, illustratively comprising butoconazole or a pharmaceutically acceptable salt or ester thereof. The composition is adapted for application in a unit dose amount to a vulvovaginal surface and has at least one nonlipoidal internal phase and at least one lipoidal external phase that is bioadhesive to the vulvovaginal surface. The composition is useful for administration to a vulvovaginal surface to treat a mixed bacterial vaginosis and vulvovaginal candidiasis infection.
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