NORMALIZATION OF PLATELET BIOMARKERS
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United States of America Patent
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Issued Date -
Jul 11, 2013
app pub date -
Nov 23, 2010
filing date -
Nov 23, 2009
priority date (Note) -
Abandoned
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Abstract
Described herein are methods useful for normalizing any biomarker in platelets. This has application in any method in which one wishes to ascertain or compare the level of a biomarker, e.g., for diagnostic or prognostic methods relating to a biomarker of interest. Using such an approach can permit the assessment of disease status (e.g., angiogenic status) of an individual with less error than an expression value that is not normalized or that is normalized to total protein levels. Also provided are methods for selecting a normalizing protein for normalizing biomarkers in a sample, e.g., a platelet sample.
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