STABILIZED PICOPLATIN ORAL DOSAGE FORM
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United States of America Patent
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N/A
Issued Date -
Jul 18, 2013
app pub date -
Aug 16, 2012
filing date -
Feb 9, 2007
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
The invention provides an oral dosage form for the anti-cancer drug picoplatin comprising a core and a coating, the dosage form being free of redox- active metal salts. The core of the tablet is a substantially dry powder comprising about 10 to 60 wt % picoplatin wherein the pieoplatin is a particulate of less than about 10 microns average particle diameter, about 40-80 wt % of a filler comprising a substantially water-soluble, water-dispersible, or water-absorbing carbohydrate, and an effective amount of up to about 5 wt % of a lubricant. The dosage form can further include a dispersant.
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