TREATMENT OF OPHTHALMIC CONDITIONS WITH FLUORENONE DERIVATIVES
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United States of America Patent
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Issued Date -
Jul 25, 2013
app pub date -
Nov 5, 2010
filing date -
Nov 12, 2009
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Abstract
Provided are compositions and methods for treatment of ophthalmic conditions, such as retinal detachment and age-related macular degeneration. Various fluorenone derivatives described herein can stimulate fluid removal from the subretinal space and down-regulate reactive gliosis. Administration of compounds described herein can provide an alternative or an adjunct to an invasive procedure to reattach the retina.
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