PHENYLPIPERIDINE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS

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United States of America Patent

APP PUB NO 20130197032A1
SERIAL NO

13823435

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a novel use of both enantiomers of the phenylpiperidine derivative OSU6162, i.e. (−) and (+)-OSU6162 as partial agonists on 5-hydroxytryptamine (5hHT) receptors. As a result, both (−) OSU6162 and (+)-OSU6162 may be used for the treatment and/or prevention of one or more diseases associated with a need for modulation of monoaminergic neurotransmitter receptors, wherein at least one of the monoaminergic neurotransmitter receptors is a 5-hydroxytryptamine receptor (5-HT receptor). Thus, said compounds act as stabilizers not only on dopaminergic, but also on serotonergic brain signaling and will act as partial agonists on such monoaminergic neurotransmitter receptors.

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Patent Owner(s)

Patent OwnerAddress
A CARLSSON RESEARCH ABGOTHENBURG GOTHENBURG VASTRA GOTALAND

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burstein, Ethan S San Diego, US 17 72
Carlsson, Lizzie Maria Goteborg, SE 1 1
Carlsson, Per Arvid Emil Goteborg, SE 3 3
Kloberg, Angélica Torslanda, SE 1 1

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