LYSOSOMAL STORAGE DISEASE ENZYMES
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United States of America Patent
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app pub date -
Apr 23, 2011
filing date -
Apr 23, 2010
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Abstract
The present invention provides compositions of recombinant human lysosomal acid lipase having particular glycosylation patterns for internalization into target cells, a vector containing the nucleic acid encoding human lysosomal acid lipase, a host cell transformed with the vector, pharmaceutical compositions comprising the recombinant human lysosomal acid lipase and method of treating conditions associated with lysosomal acid lipase deficiency.
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