RADIOLABELLED mGluR2 PET LIGANDS

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United States of America Patent

APP PUB NO 20130230459A1
SERIAL NO

13884073

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Abstract

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The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate receptor mGluR2 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo and to precursors of said compounds.

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Patent Owner(s)

Patent OwnerAddress
JANSSEN-CILAG S A EDIFICIO JOHNSON & JOHNSONPASEO DE LAS DOCE ESTRELLAS 5-7 5 PLAN TA CAMPO DE LAS NACIONES MADRID 28042

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alcázar-Vaca, Manuel Jesús Toledo, ES 19 38
Andrés-Gil, José Ignacio Toledo, ES 34 50
Bormans, Guy Maurits R Leuven, BE 11 1
Celen, Sofie Jeanne Leopoldine Leuven, BE 6 0
Cid-Núñez, José Maria Toledo, ES 24 185
Koole, Michel Leuven, BE 2 8
Trabanco-Suárez, Andrés Avelino Toledo, ES 56 167

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