Method of synergistically enhancing the therapeutic efficacy and safety of medication through a combination therapy

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United States of America Patent

PATENT NO 9119881
APP PUB NO 20130261092A1
SERIAL NO

13905888

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Abstract

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The present invention provides combinations, for treatment of subjects suffering from or at high risk of developing diseases and disorders involving expression of peroxisome proliferator-activated receptors (PPAR). The combinations include abscisic acid and one other bioactive agent, which together provide synergistic effects toward treatment or blocking of development of the disease or disorder. In exemplary embodiments, a combination of abscisic acid and a thiazolidinedione (TZD) is provided for increased insulin sensitivity and improved (i.e., reduced) obesity-induced inflammation.

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Patent Owner(s)

  • VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY;VIRGINIA POLYTECHIC INSTITUTE AND STATE UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bassaganya-Riera, Josep Blacksburg, US 46 157
Guri, Amir J Blacksburg, US 1 0
Hontecillas, Raquel Blacksburg, US 36 134

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