Comprehensive monoclonal antibody generation

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United States of America Patent

PATENT NO 10670608
APP PUB NO 20130281303A1
SERIAL NO

13977193

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Abstract

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The present invention relates to methods for efficiently generating recombinant monoclonal antibodies derived from B cells of a non-human host which has been immunochallenged with one or more target antigens. The methods comprise the steps of identifying and isolating B cell that bind to the antigen by FACS, and recombining and enriching for thousands of cells to create a B cell library. Related products and methods, such as methods of producing expression libraries, are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
BIOATLA INC11085 TORREYANA ROAD SUITE 100 SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Short, Jay M Del Mar, US 274 5063

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