METHODS AND MICROORGANISMS FOR INCREASING THE BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL ALKANES
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United States of America Patent
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Issued Date -
Oct 31, 2013
app pub date -
Apr 23, 2013
filing date -
Apr 27, 2012
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Abstract
A method of increasing the production a difunctional alkane in a microorganism that produces a difunctional alkane from alpha-keto acid by increasing the production of homocitrate in the cell relative to a wild-type or parent cell. The production of homocitrate may be obtained by engineering pathways that increase the production of alpha-ketoacid, such as alpha-ketoglutarate.
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